' 
![]()
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 7 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Iron (from Ionic Plant Based Minerals)
2 mg
10%
HSO Probiotic Blend (5 Billion CFU)¹Saccharomyces boulardii, Organic Barley Grass², Organic Oat Grass², Lactobacillus plantarum, Bacillus subtilis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus rhamnosus, Bifidobacterium breve, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus paracasei
410 mg
+
Ionic Plant Based Minerals
290 mg
+
Top Medical Research Studies
8
Lactobacillus aids chronic fatigue treatment
Role of Lactobacillus acidophilus loaded floating beads in chronic fatigue syndrome: behavioral and biochemical evidences.
High relevance for potential therapies
We explored the effects of Lactobacillus acidophilus, both free and in floating beads, as a possible treatment for chronic fatigue syndrome in a rat model. The study involved inducing fatigue through a forced swim test and then administering the probiotics over the last week of the experiment.
Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
Read More
4
Lactobacillus acidophilus shows limited effect
Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome.
Study suggests continued probiotic research
We aimed to understand if Lactobacillus acidophilus and other probiotics could help alleviate fatigue in chronic fatigue syndrome (CFS) patients. In our study with 15 participants, we first looked at their baseline fatigue prior to a four-week probiotic treatment.
While we observed some neurocognitive improvements, fatigue and physical activity levels showed no significant changes overall. Interestingly, six patients reported feeling better by the end. Our findings invite further exploration of probiotics as potential support for individuals dealing with CFS.
While we observed some neurocognitive improvements, fatigue and physical activity levels showed no significant changes overall. Interestingly, six patients reported feeling better by the end. Our findings invite further exploration of probiotics as potential support for individuals dealing with CFS.
Read More
Most Useful Reviews
9.5
Improved bowel health
5 billion of the best strains of bacteria I’ve tried. I recommend this product for those suffering from chronic fatigue syndrome. After starting, my health improved, no more constipation or bloating, and my digestion is better. I appreciate that the capsules don’t require refrigeration and are gluten-free and vegan. The inclusion of the strain Saccharomyces Boulardii is significant, as it’s highly regarded for colonic issues.
Read More
8.8
Resolved gut issues
After struggling with symptoms of chronic fatigue syndrome, I took this probiotic for three weeks. Initially, I experienced some side effects like headaches and nausea, but these subsided by week two. Now, I feel much better, my skin has cleared, and my digestive issues have significantly decreased.
Read More
8
Better digestion
I'm satisfied with this product, much better than ordinary lactic acid bacteria. It's effective for chronic fatigue syndrome, although results may vary. Give it a couple of weeks before switching to alternatives.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
8
Lactobacillus aids chronic fatigue treatment
Role of Lactobacillus acidophilus loaded floating beads in chronic fatigue syndrome: behavioral and biochemical evidences.
High relevance for potential therapies
We explored the effects of Lactobacillus acidophilus, both free and in floating beads, as a possible treatment for chronic fatigue syndrome in a rat model. The study involved inducing fatigue through a forced swim test and then administering the probiotics over the last week of the experiment.
Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
Read More
4
Lactobacillus acidophilus shows limited effect
Effect of supplement with lactic-acid producing bacteria on fatigue and physical activity in patients with chronic fatigue syndrome.
Study suggests continued probiotic research
We aimed to understand if Lactobacillus acidophilus and other probiotics could help alleviate fatigue in chronic fatigue syndrome (CFS) patients. In our study with 15 participants, we first looked at their baseline fatigue prior to a four-week probiotic treatment.
While we observed some neurocognitive improvements, fatigue and physical activity levels showed no significant changes overall. Interestingly, six patients reported feeling better by the end. Our findings invite further exploration of probiotics as potential support for individuals dealing with CFS.
While we observed some neurocognitive improvements, fatigue and physical activity levels showed no significant changes overall. Interestingly, six patients reported feeling better by the end. Our findings invite further exploration of probiotics as potential support for individuals dealing with CFS.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.6
9.5
Improved bowel health
5 billion of the best strains of bacteria I’ve tried. I recommend this product for those suffering from chronic fatigue syndrome. After starting, my health improved, no more constipation or bloating, and my digestion is better. I appreciate that the capsules don’t require refrigeration and are gluten-free and vegan. The inclusion of the strain Saccharomyces Boulardii is significant, as it’s highly regarded for colonic issues.
Read More
9.5
Pain relief
I’ve had severe abdominal discomfort associated with chronic fatigue syndrome and tried many probiotics with little relief. After three days of using Primal Defense, I noticed reduced pain and more regular bowel movements. Now, I feel healthier overall.
8.8
Resolved gut issues
After struggling with symptoms of chronic fatigue syndrome, I took this probiotic for three weeks. Initially, I experienced some side effects like headaches and nausea, but these subsided by week two. Now, I feel much better, my skin has cleared, and my digestive issues have significantly decreased.
Read More
8.8
Less IBS symptoms
Amazing help with my chronic fatigue syndrome. I increased my intake to two capsules daily and greatly reduced IBS symptoms, experiencing less gas and better digestion.
8
Better digestion
I'm satisfied with this product, much better than ordinary lactic acid bacteria. It's effective for chronic fatigue syndrome, although results may vary. Give it a couple of weeks before switching to alternatives.
